Gene IRAK-Un_dd (S.moellendorffii)

IRAK-Un_dd

Species: S.moellendorffii
Alias: IRAK-Un_dd
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_dd.AA Protein None 136 None Fasta, JSON
IRAK-Un_dd.NA RNA None 411 None Fasta, JSON
IRAK-Un_dd.kin_dom Protein Kinase Domain None 32 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_dd.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_dd.AA TKL 27-59 29 1.7e-07 23.05 In-house 161-207 (364) Show / Hide 
Range on Protein: 27-59
Range on HMM: 161-207/364
Sequence Identity: 29% (14 aa)

IIRRDLRPHNILLTHDYA--------------PMVGDFGLARWHTSS
|| ||| ..|||.  ..               . ..||||.|... |
IIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQS
Kinase IRAK-Un_dd.AA RAF 27-54 50 1e-06 17.11 In-house 124-151 (282) Show / Hide 
Range on Protein: 27-54
Range on HMM: 124-151/282
Sequence Identity: 50% (14 aa)

IIRRDLRPHNILLTHDYAPMVGDFGLAR
|| |||.  ||.|  |    .|||||..
IIHRDLKSNNIFLHEDMTVKIGDFGLMT
Kinase IRAK-Un_dd.AA CMGC 30-55 32 4e-06 15.31 In-house 208-253 (513) Show / Hide 
Range on Protein: 30-55
Range on HMM: 208-253/513
Sequence Identity: 32% (15 aa)

RDLRPHNILLTHDYAP--------------------MVGDFGLARW
||| | |||..|.                        ..|||||||
RDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARW
Kinase IRAK-Un_dd.AA NEK-Unclassified 27-54 57 8e-06 14.92 In-house 118-145 (258) Show / Hide 
Range on Protein: 27-54
Range on HMM: 118-145/258
Sequence Identity: 57% (16 aa)

IIRRDLRPHNILLTHDYAPMVGDFGLAR
|| |||.| || || |     |||| .|
IIHRDLKPQNIFLTDDDTVSMGDFGISR
Kinase IRAK-Un_dd.AA NEK10 27-54 42 9e-06 14.79 In-house 141-168 (279) Show / Hide 
Range on Protein: 27-54
Range on HMM: 141-168/279
Sequence Identity: 42% (12 aa)

IIRRDLRPHNILLTHDYAPMVGDFGLAR
|. |||.| ||... .    . |||||.
IVHRDLTPNNIMMGDKDRVTITDFGLAK
Kinase IRAK-Un_dd.AA CDK-Unclassified 27-54 39 1.4e-05 14.16 In-house 142-174 (324) Show / Hide 
Range on Protein: 27-54
Range on HMM: 142-174/324
Sequence Identity: 39% (13 aa)

IIRRDLRPHNILLTHDY---APMV--GDFGLAR
|. ||. | ||..|.     .||.  .|||.|.
IMHRDIKPQNIMITNNNSTVSPMLKIADFGQAC
Kinase IRAK-Un_dd.AA CDK4 27-54 60 1.9e-05 14.42 In-house 131-158 (290) Show / Hide 
Range on Protein: 27-54
Range on HMM: 131-158/290
Sequence Identity: 60% (17 aa)

IIRRDLRPHNILLTHDYAPMVGDFGLAR
|| ||| | |||.| |      ||||||
IIHRDLKPQNILVTSDGHVKLADFGLAR
Kinase IRAK-Un_dd.AA ERK7 25-54 56 3.3e-05 13.43 In-house 119-148 (292) Show / Hide 
Range on Protein: 25-54
Range on HMM: 119-148/292
Sequence Identity: 56% (17 aa)

GTIIRRDLRPHNILLTHDYAPMVGDFGLAR
| .| |||.| ||||  .    | ||||||
GNVIHRDLKPSNILLDSECMVKVCDFGLAR
Kinase IRAK-Un_dd.AA MLK 26-61 33 3.4e-05 14.11 In-house 147-194 (291) Show / Hide 
Range on Protein: 26-61
Range on HMM: 147-194/291
Sequence Identity: 33% (16 aa)

TIIRRDLRPHNILLTH------DYAPMVGDFGLAR-WHTS-----SQP
.||.||| .||||...      .    . |||..| ||..     |..
PIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNA
Kinase IRAK-Un_dd.AA CAMK 27-54 28 5.4e-05 11.25 In-house 200-244 (425) Show / Hide 
Range on Protein: 27-54
Range on HMM: 200-244/425
Sequence Identity: 28% (13 aa)

IIRRDLRPHNILLTHD-----------------YAPMVGDFGLAR
|. ||| | ||||...                 .   . |||.|.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFAN
Kinase IRAK-Un_dd.AA Pkinase 30-61 33 0.000827 14.55 Pfam 132-168 (293) Show / Hide 
Range on Protein: 30-61
Range on HMM: 132-168/293
Sequence Identity: 33% (13 aa)

RDLRPHNILLTHDYAP----MVGDFGLAR---WHTSSQP
||| | |||. ... .     ..|||||.   .  .| .
RDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-M