Gene IRAK-Un_cz (S.moellendorffii)

IRAK-Un_cz

Species: S.moellendorffii
Alias: IRAK-Un_cz
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_cz.AA Protein None 548 None Fasta, JSON
IRAK-Un_cz.NA RNA None 1647 None Fasta, JSON
IRAK-Un_cz.kin_dom Protein Kinase Domain None 189 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_cz.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
CLECT IRAK-Un_cz.AA CLECT 27-154 18 1.6e-17 65.48 SMART 1-141 (141) Show / Hide 
Range on Protein: 27-154
Range on HMM: 1-141/141
Sequence Identity: 18% (32 aa)

C---PDGWLRGPA------DRCFMLVNASSTWEESETSCRNRS--------GHLASITSDAEVAFVKGHCTGVFDPCWVGAVISNTSRGVLWRWSDCH--
|   |.|| . |       ..|. ...    |.... .|..          ||||||.| .| .||  .        |.|.          |.|||    
CPHCPPGWNWYPRPNKYFGGHCYKFFT----WHDAQQFCQSMGPWTHRVQGGHLASIHSQEENDFVQSL-------YWIGLH-------G-WQWSDGSGW

----VRWN-FSFASSN--------------CSSSGCVNLGEYCLSVSSMRGLVRENCGD-----RHRFVCV
    ..|. ...  ..               .. .|| .               .||..     .|.|.| 
IPPTNPWVDYTNWAPGYPNNQPNNWWRHGNGGNGNCVYMW-----------WNDVNCNSNDPYHKHPFICK
Lectin_C IRAK-Un_cz.AA Lectin_C 45-78 32 7e-06 27.92 Pfam 1-40 (122) Show / Hide 
Range on Protein: 45-78
Range on HMM: 1-40/122
Sequence Identity: 32% (13 aa)

ASSTWEESETSCRNRSGH--LASITSDAEV----AFVKGH
 . ||.|... |... ||  |.|| | .|     .|.. |
ERMTWHEAQAYCQKMGGHCHLVSIHSQEEQMFIWDFITQH
Lectin_C IRAK-Un_cz.AA Lectin_C 128-155 22 11.509297 2.52 Pfam 92-122 (122) Show / Hide 
Range on Protein: 128-155
Range on HMM: 92-122/122
Sequence Identity: 22% (7 aa)

GEYCLSVSSM---RGLVRENCGDRHRFVCVL
.|.| .....     .  |.|.  |..||  
NEDCVHMWTDTNWGKWNDEHCDWKHPWVCEF
Kinase IRAK-Un_cz.AA TKL 242-500 18 4.7e-45 155.99 In-house 7-364 (364) Show / Hide 
Range on Protein: 242-500
Range on HMM: 7-364/364
Sequence Identity: 18% (68 aa)

GSTFKGILSD---------GVLVAVKKLERSSFQSR---------------------------KEFLAEMNRIARLRHPSLVAVIGCCYDHGE-------
|  .||..           |  |||||. . . ...                           ...  |.. . ||||| .|  .|.| . .        
GEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHP

------RYIAYEYIANGPLDLWLHDPVRRGTLDWRTRMQIAVTAAQGIAYLHDQV-----KPHVIHRDIKASSILLDDKFH--------------GRVMG
       .| .||. .| |   ||         |  |...|  .|.|..||| .      || .||||.| . ||.|....                .  
VGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICD

VGLASVVPWEAAYE------------------RTVVAGTHGYLAPEFVYRN----------------ELTTKSDVYSFGVLMLELISGRKPAMPVDVVDW
 ||. .. ..   .                  .  . || ...|||    .                | ..|.||||||... |......         .
FGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--------PY

QTIFEWATP------LVQSQQLQEIIDPSLTSIPA--------PAHIQMLVDLIYSCTQHVASMRPRMSYVVHQL
. . .          . ...  ..   | . .|.         |   . . .|.  | .| .. || .. ....|
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-Un_cz.AA TK 242-500 14 9.2e-31 99.76 In-house 13-486 (486) Show / Hide 
Range on Protein: 242-500
Range on HMM: 13-486/486
Sequence Identity: 14% (71 aa)

G---STFKGILSDG--------------------------VLVAVKKLE---RSSFQSRKE-----------FLAEMNRIARLR-----HPSLVAVIGCC
|     .||.. ..                          . |||| |     .| . ...           ||.|.. .. ..     || .|  .|.|
GSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVC

YDH------------GERYIAYEYIANGP----LDLWLHDPVRRGT------------------------------------------------------
 ..            .  .|  || ..|     |. .|..  ....                                                      
TQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPL

-------------------LDWRTRMQIAVTAAQGIAYLHDQ----VKPHVIHRDIKASSILLDDKFH-----------GRVMGVG--------LASVVP
                   |. .... ... .|.| .|||..    . ....|||. |  .|.... .            ..   |        ||  ..
TTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIY

WEAAYERTVVAGTHG-------------------------YLAPEFVYRNE---------LTTKSDVYSFGVLMLELIS-G-RKPA--MPV-----DVVD
 .  | |.   || .                         ..||| .  ..          ||||||.|||||| |. . |   ..  |.      |   
SDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKD---

WQTIFEWATPLVQSQQLQEIIDPSLT------------------SIPAPAHI-------------QMLVDLIYSCTQHVASMRPRMSYVVHQL
               ..||...   .                    |. ..              ... ||. .| .. .. ||..| ...||
-------------G-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-Un_cz.AA TKL-Unique 255-427 27 1.5e-25 87.13 In-house 23-224 (290) Show / Hide 
Range on Protein: 255-427
Range on HMM: 23-224/290
Sequence Identity: 27% (55 aa)

VAVKKLER---SSFQSRKEFLAEMNRIARLR-HPSLVAVIGCCY----DHGERYIAYEYIANGPLDLWLHD-------PVRRGTLDWRTRMQIAVTAAQG
||.|...    ||.....||  | | . .|. || .|  .| |     . ....|  ||.  | |.  ||.         .  .|..  |...|  .|||
VAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQG

IAYLHDQVKPHVIHRDIKASSILLDDK-----FHGRVMGVGLASVVP--WEAAYERT------VVAGTHGYLAPEFVYR--NELTTKSDVYSFGVLMLEL
  |||   .| .||||.| |..|.| .     .  .. ..||. .     .  . .       .. |.  ..|||   .  .  ..||||||||. . |.
MYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEI

ISG
...
ATR
Kinase IRAK-Un_cz.AA Pkinase 250-428 25 5.9e-23 82.24 Pfam 22-209 (293) Show / Hide 
Range on Protein: 250-428
Range on HMM: 22-209/293
Sequence Identity: 25% (49 aa)

SDGVLVAVKKLERSSFQS--RKEFLA--EMNRIARLRHPSLVAVIGCCYDHGERYIAYEYIANG----PLDLWLHDPVRRGTL--DWRTRMQIAVTAAQG
..| .||||......  |  ... .   |    .||.||  |  .....|... |.  ||  .|     |  ...   |.|..  ....   ..   ..|
GTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRG

IAYLHDQVKPHVIHRDIKASSILLDDKFHG----RVMGVGLASVVPWEAAYERTVVAGTHGYLAPEFVY-RNELTTKSDVYSFGVLMLELISGR
..|.|..    .||||.| . ||.|.. |     ..   ||| .. .      |...|| .|.||| .  ... ..|.|..|.|... |...||
LEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR
Kinase IRAK-Un_cz.AA Frk 242-425 30 3.3e-22 73.47 In-house 13-196 (260) Show / Hide 
Range on Protein: 242-425
Range on HMM: 13-196/260
Sequence Identity: 30% (58 aa)

GSTFKGILSDGVLVAVKKLERSSFQSRKEFLAEMNRIARLRHPSLVAVIGCCYDHGERYIAYEYIANGPLDLWLHDPVRRGT-LDWRTRMQIAVTAAQGI
|  . |     . ||||.|   .    ..||.|   . .|||| |. .   |      ||  | . .| |  .|    ..|  .  .. ...|   | |.
GEVWEGLWNNTTPVAVKTLKPGTMDP-NDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQLVDMAAQVAAGM

AYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWEAA--YERTVVAGTH-GYLAPEFVYRNELTTKSDVYSFGVLMLELI
||| .|     ||||. |  .|....   ..   ||| |.  .    ||  . |     . ||| .  |. |.||||.|||.|. |.|
AYLESQ---NYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEII
Kinase IRAK-Un_cz.AA TK-Unique 241-426 26 4.7e-20 65.95 In-house 17-234 (294) Show / Hide 
Range on Protein: 241-426
Range on HMM: 17-234/294
Sequence Identity: 26% (58 aa)

RGSTFKGI--LSDGVLVAVKKLE-RSSFQSRKEFLAEMNRIARLR-HPSLVAVIGCCYDHG-ERYIAYEYIANGPLDLWLH--DPVRRGT----------
||  ....   .. . ||||.|. .........|| | .    |  || .|  .||| . .   .|..||...| |.  |.   |..|..          
RGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDF

-----------LDWRTRMQIAVTAAQGIAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWEAAYERTV--VAGTHGYLAPEFVY--RNEL
           .. ..  ..|.  |.| .||. | | ...|||. |. .|| ...   . . |.|  |  . .|...       . ..|||  .  ..  
HHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRK-KIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMY

-TTKSDVYSFGVLMLELIS
 ||||||.|||||| |. .
HTTKSDVWSFGVLMWEIFT
Kinase IRAK-Un_cz.AA STE 242-428 19 2.6e-19 64.92 In-house 13-265 (359) Show / Hide 
Range on Protein: 242-428
Range on HMM: 13-265/359
Sequence Identity: 19% (53 aa)

GSTFKGILSD----------------GVLVAVKKLERSSF-----------------QSRKEFLAEMNRIARLR--HPSLVAVIGCCYDHG-------ER
|...|..  .                |...|.|... ..                  . ....| |..   ...  ||  |  .||... |       | 
GTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDEL

YIAYEYIANGPLDLWLH-DPVRRGTLDWRT-------RMQIAVTAAQ---G-IAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLA------SVVP
.|. ||...| ||  ..    . ..|.            |||. . |   |  .|||..    .||||||.. |||          | |.      ....
WICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VKLCDFGVCGQLTD

--------------WEAAYERTVVAGTHGYLAPEFVYR------NELTTKSDVYSFGVLMLELISGR
                 . .|. ..||  . ||| . .      .. .||.|..|.| ...|.. |.
SMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase IRAK-Un_cz.AA Pkinase_Tyr 245-356 29 9.8e-19 64.08 Pfam 16-137 (270) Show / Hide 
Range on Protein: 245-356
Range on HMM: 16-137/270
Sequence Identity: 29% (37 aa)

FKGILS-----DGVLVAVKKL-ERSSFQS--RKEFLAEMNRIARL-RHPSLVAVIGCCYDHGER---YIAYEYIANGPLDLWLHDP-VRRGTLDWRTRMQ
.||..      ... ||||.| | .. .   |..|..|..    | .|| .|  .|.|.|.||    ||  || ..| |.  |...   .. |.  .  |
YKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQ

IAVTAAQGIAYLHDQVKPHVIHRDI
...  |.| .||...   . ||||.
MCWQIAKGMEYLESK---NCIHRDL
Kinase IRAK-Un_cz.AA IRAK 245-367 30 3.1e-18 61.34 In-house 16-150 (317) Show / Hide 
Range on Protein: 245-367
Range on HMM: 16-150/317
Sequence Identity: 30% (41 aa)

FKGILSDGV-LVAVKKLER----SSFQSRKEFLA---EMNRIARLRHPSLVAVIGCCYDHGERYIAYEYIANGPLDLWLHDPVRRGT---LDWRTRMQIA
..| ..     .|||||      |  .....|..   |.   .|.||| .|.. | |.. ..    |.|..|| |   |.     ..   | | .|  |.
YRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSIC

VTAAQGIAYLHDQV-KPHVIHRDIKASSILLDDKF
  .| || .||.   .  .||.||| . ||||. |
WGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHF
Kinase IRAK-Un_cz.AA Dicty4-Unclassified 330-430 34 3.2e-18 58.96 In-house 112-207 (263) Show / Hide 
Range on Protein: 330-430
Range on HMM: 112-207/263
Sequence Identity: 34% (35 aa)

MQIAVTAAQGIAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWEAAYERTVVAGTHGYLAPEFVYRNELTTKSDVYSFGVLMLELISGRK
. .|   |||...||      .||||||.| ||.|  |  ..   |.. |.  .  .  | .|||    .||       . ||||||..... ||. |  
IKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVI--DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDE

P
|
P
Kinase IRAK-Un_cz.AA MLK 255-372 24 8.9e-17 54.83 In-house 30-172 (291) Show / Hide 
Range on Protein: 255-372
Range on HMM: 30-172/291
Sequence Identity: 24% (35 aa)

VAVKKLE---RSSFQS----RKEFLAEMNRIARLRHPS----LVAVIGCCYDHGE-RYIAYEYIANGPLDLWLHD-PV----------RRGTLDWRTRMQ
||||. .   . . ..    ...|  | .. ..|.||      ... |.| ...   .|  ||...|.|   ||. .           . .. |    |.
VAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMN

IAVTAAQGIAYLHDQVKPHVIHRDIKASSILLDD---KFHGRVM
.|.  |.|..||| . .. .||||.| . ||.|.    .|....
WALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTL
Kinase IRAK-Un_cz.AA TyrKc 242-500 21 3.1e-16 39.73 SMART 13-280 (280) Show / Hide 
Range on Protein: 242-500
Range on HMM: 13-280/280
Sequence Identity: 21% (63 aa)

GSTFKGILSDGVLVAVKKLERSSFQSRKEFLAEMNRIARL--RHPSLVAVIGCCYDH-------GERYIAYEYIANGPLDLWLHDPVRRGTLDWRTRMQI
|  .||...  . ||||.|  ..   |..|. |..   .|  .|| .|. .|.| ..       .  .|  || ..| |.  |... ..  | ...  ..
GEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--LCMKDLLSF

AVTAAQGIAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWE----AAYERTVVA---GTHG-----YLAPEFVYRNELTTKSDVYSFGVL
.. .|.| .|||..   ..||||. |  .|...... ..   ||.  .  .    .. .  ...   |...      .|||    .. ||||||.||||.
CWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVC

MLELISGRKPAMPVDV-----VDWQTIFEWATPLVQSQQLQEIIDPSLTSIPAP-----AHIQMLVDLIYSCTQHVASMRPRMSYVVHQL
| |. .    ..|        ...| ..|.    |..    .. .  .     |     ..  |   .. .| .. ...||..| .....
MWEIFTY--GQQPYPGMIQQMMSNQEVIEY----VKQGYRMPQPPNDY-----PMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
S_TKc IRAK-Un_cz.AA S_TKc 234-503 19 8.4e-16 54.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 234-503
Range on HMM: 1-231/231
Sequence Identity: 19% (55 aa)

FGMENRLR----GSTFKGILSD-GVLVAVKKLERSSFQSRKEFLAEMNRIARLRHPSLVAVIGCCYDHGERYIAYEYIAN--GPLDLWLHDPVRRGT---
. . . .     |. .|..  . | .||.|..        . .. |..   . .|| .|  .....| .. |.  ||. .  | |   ...  |.|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWRTRMQIAVTAAQGIAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWEAAYERTVVAGTHGYLAPEFVYRNELTT-KSDVYSFGVLML
..  .   ..   .....|.|..   ..||||.| . ||||.  |  .   ||| ..        | . ||  |.||| .     .. |.|..|.|... 
FPE-HARFYMYQICCALEYCHSH---GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELISGRKPAMPVDVVDWQTIFEWATPLVQSQQLQEIIDPSLTSIPAPAHIQMLVDLIYSCTQHVASMRPRMSYVVH------QLDQL
|...|. |       . |..|.                            . . |.|  | |   . ||    . .      .   .
EMLCGYPPFP-----QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-Un_cz.AA IRAK 390-431 43 2.2e-13 43.94 In-house 181-224 (317) Show / Hide 
Range on Protein: 390-431
Range on HMM: 181-224/317
Sequence Identity: 43% (19 aa)

VVAGTHGYLAPEFVY--RNELTTKSDVYSFGVLMLELISGRKPA
.| ||  |..||| .    .||.|.||||||.  ||...|....
HVRGTTWYMPPEFIRDPQGQLTKKTDVYSFGIVLLEVLTGCRAV
Kinase IRAK-Un_cz.AA LRRK 280-363 33 1.9e-12 40.33 In-house 113-199 (351) Show / Hide 
Range on Protein: 280-363
Range on HMM: 113-199/351
Sequence Identity: 33% (30 aa)

RLRHPSLVAVIGCCYDHGERYIAYEYIANGPLDLWLHDPVRRG------TLDWRTRMQIAVTAAQGIAYLHDQVKPHVIHRDIKASSILL
.|.||..|  .| | ..  . .. ||. .| |.  ||.. . |       ..| .. .||.  | |..|||.. .| .|||| |   |||
HLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH-NPPIIHRDLKSPNILL
Kinase IRAK-Un_cz.AA LRRK 391-430 38 1.3e-08 26.53 In-house 239-282 (351) Show / Hide 
Range on Protein: 391-430
Range on HMM: 239-282/351
Sequence Identity: 38% (17 aa)

VAGTHGYLAPEFVYRN---ELTTKSDVYSFGVLMLELISGR-KP
. |. |..||| .  |   | |.|.|.||||... ||....  |
CVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase IRAK-Un_cz.AA MLK 392-430 33 9.3e-07 19.61 In-house 194-235 (291) Show / Hide 
Range on Protein: 392-430
Range on HMM: 194-235/291
Sequence Identity: 33% (14 aa)

AGTHGYLAPEFV---YRNELTTKSDVYSFGVLMLELISGRKP
|||  . |||       .  . |.||.|.||.. |..... |
AGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAK-Un_cz.AA Pkinase_Tyr 398-430 52 4e-06 21.33 Pfam 181-214 (270) Show / Hide 
Range on Protein: 398-430
Range on HMM: 181-214/270
Sequence Identity: 52% (18 aa)

LAPEFVYRNELTTKSDVYSFGVLMLELIS-GRKP
.|||    .. ||||||.|||||| |... |..|
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase IRAK-Un_cz.AA LRRK 474-502 44 1.2e-05 15.99 In-house 323-351 (351) Show / Hide 
Range on Protein: 474-502
Range on HMM: 323-351/351
Sequence Identity: 44% (13 aa)

MLVDLIYSCTQHVASMRPRMSYVVHQLDQ
|. ||| .| ||    || .|..| .| |
MYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAK-Un_cz.AA Dicty4-Unclassified 255-293 34 1.3e-05 15.1 In-house 25-67 (263) Show / Hide 
Range on Protein: 255-293
Range on HMM: 25-67/263
Sequence Identity: 34% (15 aa)

VAVKKLERSSFQSR----KEFLAEMNRIARLRHPSLVAVIGCC
|||||.   .|. |    ..|..|      . || || . | |
VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC
Kinase IRAK-Un_cz.AA TK-Unique 478-500 34 0.00015 11.75 In-house 272-294 (294) Show / Hide 
Range on Protein: 478-500
Range on HMM: 272-294/294
Sequence Identity: 34% (8 aa)

LIYSCTQHVASMRPRMSYVVHQL
|..||.|.....||  . ..|.|
LMKSCWQWEPEERPSFRQIKHRL
Kinase IRAK-Un_cz.AA Pkinase_Tyr 477-500 33 0.159921 5.78 Pfam 247-270 (270) Show / Hide 
Range on Protein: 477-500
Range on HMM: 247-270/270
Sequence Identity: 33% (8 aa)

DLIYSCTQHVASMRPRMSYVVHQL
||. .| .. ...||..|....||
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase IRAK-Un_cz.AA MLK 475-500 23 0.211658 0.78 In-house 266-291 (291) Show / Hide 
Range on Protein: 475-500
Range on HMM: 266-291/291
Sequence Identity: 23% (6 aa)

LVDLIYSCTQHVASMRPRMSYVVHQL
.  |.  | .  .. || ....| .|
WKKLMKQCWNQDPHKRPSFRQIVQHL