Gene IRAK-0_d-1 (S.moellendorffii)

IRAK-0_d-1

Species: S.moellendorffii
Alias: IRAK-0_d-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-0

Sequence

Name Sequence Type Origin Length Description Download
IRAK-0_d-1.AA Protein None 885 None Fasta, JSON
IRAK-0_d-1.NA RNA None 2658 None Fasta, JSON
IRAK-0_d-1.kin_dom Protein Kinase Domain None 193 None Fasta, JSON

Protein domain

Protein domains of IRAK-0_d-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 IRAK-0_d-1.AA LRR_1 413-434 37 0.002724 15.84 Pfam 1-26 (26) Show / Hide 
Range on Protein: 413-434
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

GLNILDLRN-N--SLSGSIPD--MSRL
 | .|||.. |  .|.|.||.     |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-0_d-1.AA LRR_1 436-458 33 0.02915 12.19 Pfam 1-26 (26) Show / Hide 
Range on Protein: 436-458
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

VLRQLHLES-N--RLSGDFPES-LQNI
 |. |.| . |  .|.|..|.| . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-0_d-1.AA LRR_1 460-482 37 0.047442 11.44 Pfam 1-26 (26) Show / Hide 
Range on Protein: 460-482
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

TLQLLYIQN-N--LLTGSIPED-LLNR
.|| |.... |   |||.||.. . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase IRAK-0_d-1.AA TKL 555-820 21 8.4e-64 218.28 In-house 1-364 (364) Show / Hide 
Range on Protein: 555-820
Range on HMM: 1-364/364
Sequence Identity: 21% (82 aa)

IGSGGFGTVYYGRLKN---------GREVAIKVLSATS--------------------------HQGAREFSNEVT-LLSRIHHRNLVSFLGFCQEGRE-
|||||||.|| |....         |..||.|... ..                           . .|.| .|.. ..||..| |.|.|.|.|....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RILVYEFMHIGT-LRDCLYGKEEDRLVLDWTSRLKVLLDAAKGLDYLHT------GCNPSIIHRDVKSSNILISDKKT----------
              .|.|... |. | . .           |  |..  ||.|.|..|||.      .  | ||||| ||.|||. .. |          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----GKVADFGLSKMTSEGSSLVSTT------------------VKGTVGYLDPEYYMNQ----------------RLTEKSDVYSFGIVLLETISAREP
     |..|||||.. |. ..   |                   . || ... ||  ..|                  .||.||||||||| | .. .. 
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-

LSPELFEPESNIVQWARA------ALQKGDIKSIVDPALGDAPR-------MESLWK-VGEIAMYCVEPHGVNRPTMAEVAREL
       |....    .       . ......    | . . ..        .. .. . .... | ..   .||.. |.  .|
-------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-0_d-1.AA Dicty4 550-743 37 1.9e-53 176.66 In-house 2-209 (277) Show / Hide 
Range on Protein: 550-743
Range on HMM: 2-209/277
Sequence Identity: 37% (78 aa)

NFGNKIGSGGFGTVYYGRLKNGREVAIKVL----SATSHQGAREFSNEVTLLSRIHHRNLVSFLGFCQ----EGRERILVYEFMHIGTLRDCLYG---KE
|....||.|.||.|| |. . | |||.|.|       .     || .||.... | | |.. |.| |     .  .   | |.|. |.|   |       
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

EDRLVLDWTSRLK---VLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEGSSLVS--TTVKGTVGYLDPEYYMNQRLTEKSD
 ..  |||. ...     .|||.|. .||. ||| ||||| ||.|.|... .. ||.|||||..  .....    .|..||...  ||  |.|. .||.|
QQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSFGIVLLE
|||||||| |
VYSFGIVLWE
Kinase IRAK-0_d-1.AA IRAK 550-746 34 3.5e-49 169.71 In-house 2-219 (317) Show / Hide 
Range on Protein: 550-746
Range on HMM: 2-219/317
Sequence Identity: 34% (75 aa)

NFGNKIGSGGFGTVYYGRLKNGR-EVAIK----VLSATSHQGAREFSN---EVTLLSRIHHRNLVSFLGFCQEGRERILVYEFMHIGTLRDCLYGKEEDR
. .|.||.||||.|| |..||    .|.|    . . .  .  ..|     |. ...|..| |.|...|.| |. .  |||..|  |.|.| | .   . 
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC

LV--LDWTSRLKVLLDAAKGLDYLHTGC-NPSIIHRDVKSSNILISDKKTGKVADFGLSKM---TS--EGSSL---VSTTVKGTVGYLDPEYYM--NQRL
    | |  |..... .|.|. .||.     .|||.|.||.|||  .  | | .||||      .|  | ...      .|.||  |. ||.      .|
PPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQL

TEKSDVYSFGIVLLETIS
| |.|||||||||||...
TKKTDVYSFGIVLLEVLT
Kinase IRAK-0_d-1.AA TKL-Unique 551-743 35 1.1e-47 164.73 In-house 1-220 (290) Show / Hide 
Range on Protein: 551-743
Range on HMM: 1-220/290
Sequence Identity: 35% (79 aa)

FGNKIGSGGFGTVYYGRLKNGREVAIKVLSA---TSHQGAREFSNEVTLLSRIH-HRNLVSFLGFCQ----EGRERILVYEFMHIGTLRDCLY------G
|.||||.||.|.|| |   .| .||||...     | .  .||.|||......| | |.| . |.|        ....| |..  |.|.| |        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

KEEDRLVLDWTSRLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDK-----KTGKVADFGLSKMTSEGSSLVST--------TVKGTVGYLDPEYY
  .. . |..  |.|  .|.|.|..|||.   | ||||| ||||.|.. .        |..||||||  |  .   ..        |..|.  .. ||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

MN--QRLTEKSDVYSFGIVLLE
..     .|||||||||||| |
RMNFCQYSEKSDVYSFGIVLWE
Kinase IRAK-0_d-1.AA DRK 550-743 37 6.5e-43 143.18 In-house 2-194 (258) Show / Hide 
Range on Protein: 550-743
Range on HMM: 2-194/258
Sequence Identity: 37% (76 aa)

NFGNKIGSGGFGTVYYGRLKNGREVAIKVLSATSHQ---GAREFSNEVTLLSRIHHRNLVSFLGFCQEGRERILVYEFMHIGTLRDCLYGKEEDRLVLDW
  || || |..| |. |    | .||.| | .          ||  |..|...  | | . |.| | .  .   . |.|  | |   |    .. . .||
KIGNRIGRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH---DESIEMDW

TSRLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSK----MTSEGSSLVSTTVKGTVGYLDPEYYMNQRLTEKSDVYSFGIVLL
  ...  .|.|||. ||| .||| ||||| || | |. .    ||||||||     . . .      |  || .   ||   ||| ||| |||||.||| 
PLMKQMMFDCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHK---FAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLW

E
|
E
Kinase IRAK-0_d-1.AA LRRK 549-741 27 8e-39 134.97 In-house 1-272 (351) Show / Hide 
Range on Protein: 549-741
Range on HMM: 1-272/351
Sequence Identity: 27% (75 aa)

NNFGNKIGSGGFG-TVYYGRLKN---------------------------GREVAIKVLSAT----------------------------------SHQG
  ....||.|||| .|| .....                           . .||||..  .                                  ..  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

AREFSNEVTLLSRIHHRNLVSFLGFCQEGRERILVYEFMHIGTLRDCLYGKEEDRL-----VLDWTSRLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNI
 ||| .||...|. .| |.|| .|||   . ...| |.. .|.| . |  |..|..     ...|. .||. |. |||..|||  .||.||||| || ||
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LI-SDK-----------KTGKVADFGLSK-MTSEGSSLVSTTVKGTVGYLDPEYYMNQ---RLTEKSDVYSFGIVL
|. | .            . |.||||.|   .. ....... | |. |.. ||   .      |||.|.||||..|
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV-GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Pkinase IRAK-0_d-1.AA Pkinase 549-762 26 3e-38 136.34 Pfam 1-221 (293) Show / Hide 
Range on Protein: 549-762
Range on HMM: 1-221/293
Sequence Identity: 26% (61 aa)

NNFGNKIGSGGFGTVYYGRLKNGRE-VAIKVLSATSHQGAREFSN-----EVTLLSRIHHRNLVSFLGFCQEGRERILVYEFMHIG----TLRDCLYGKE
  .| |||||.||.|| .. |. .. ||.|...   |.   .  .     |. .. |..| | | ..........  .| |..  |     | | . ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

EDRLVLDWTSRLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTG----KVADFGLSK-MTSEGSSLVSTTVKGTVGYLDPEYYM-NQRLTEKS
. .. ...    ....  ..||.|.|  .  .|||||.|..||||... .     |..||||.| .  . ..   ||. || .|. ||  . .|  . |.
HGCFYFSEWECKFYMYQILRGLEYCHS-M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSFGIVLLETISAREPLSPELFEPESNI
|..|.|..| | .. | | . .   ... .
DMWSCGCILYEMLCGRPPFPGHC-WHDN-H
Kinase IRAK-0_d-1.AA Pkinase_Tyr 550-750 28 1.3e-37 128.02 Pfam 2-214 (270) Show / Hide 
Range on Protein: 550-750
Range on HMM: 2-214/270
Sequence Identity: 28% (62 aa)

NFGNKIGSGGFGTVYYGRLK-----NGREVAIKVLSATSHQGA---REFSNEVTLLSRI-HHRNLVSFLGFCQ-EGRE--RILVYEFMHIGTLRDCLYGK
 || |.|.| ||.|| |..|     .. .||.|.|  .... .   ..| .|. ... . || |.|...| |  .|.    ..| |.|  | |.| |  .
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

--EEDRLVLDWTSRLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMT-SEGSS-LVSTTVKGTVGYLDPEYYMNQRLTEKSD
  ....| . .   |.  .. |||..||.      .||||.   |.|...... |..||||..   ...    ...  |  .  . ||  .. . |.|||
REDKQPLTMKD--LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VYSFGIVLLETIS-AREP
|.|||... | ..  ..|
VWSFGVLMWEIFTYGEQP
Kinase IRAK-0_d-1.AA TK 549-755 16 7.2e-37 120.59 In-house 1-399 (486) Show / Hide 
Range on Protein: 549-755
Range on HMM: 1-399/486
Sequence Identity: 16% (66 aa)

NNFGNKIGSGGFG---TVYYGRLKNGR--------------------------EVAIKVLSATSHQGAREFSN-----------------EVTLLS--RI
  .|.|.|.| ||   .|| |......                          .||.|.| ..... ..||                   |  ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHRNLVSFLGFCQEGRE------------RILVYEFMHIGT----LRDCLYGKEEDRLV-----------------------------------------
|| |.|...| | .|..             ..| |.|. |     ||| |  . ...                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWTSRLKVLLDAAKGLDYLHTG----CNPSIIHRDVKSSNILISDKKT-----------GKVADFGLS
                               |.   .|   ...|.|. |||        . ..|||.   |.|......            |.||||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-----MTSEGSSLVSTTVKGTVG----------------------------YLDPEYYM---------NQRLTEKSDVYSFGIVLLETIS-AREPLSPE
.     .. .  |    ..|.. |                            .. ||  .         . . |.||||.|||... |  . ..||  ..
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

L
.
M
Kinase IRAK-0_d-1.AA MLK 549-750 29 8.3e-37 125.25 In-house 1-235 (291) Show / Hide 
Range on Protein: 549-750
Range on HMM: 1-235/291
Sequence Identity: 29% (69 aa)

NNFGNKIGSGGFGTVYYGRLKNGR----EVAIKVLS------ATSHQGAREFSNEVTLLSRIHHRN----LVSFLGFCQE-GRERILVYEFMHIGTLRDC
 .|  .||||.|| |. || .| .    .||.|         . .   ...|  |. .|... |.|     . |.| |.. . .  .| |..  | | . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LYG---KEEDR-------LVLDWTSRLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISD------KKTGKVADFGLSKMTSEGSSLVSTTVKGTVGY
|.|   |..|.        | |  . ..  |. |.|..|||    . ||||| ||.||||..      ..| |..|||.|.. ..      .  .||. .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

LDPEYY---MNQRLTEKSDVYSFGIVLLETISAREP
  ||      ... .||.||.|.|.|| | .. ..|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAK-0_d-1.AA CZAK 550-750 32 1.5e-36 127.76 In-house 2-221 (279) Show / Hide 
Range on Protein: 550-750
Range on HMM: 2-221/279
Sequence Identity: 32% (73 aa)

NFGNKIGSGGFGTVYYGRLKNGREVAIKVLSATSHQGARE------FSNEVTLLSRIHHRNLVSFLGFCQEGR--ERILVYEFMHIGTLRDCLYGKEEDR
 ||  || | || || .. . |  |||| .   .     |      | .||  .|   | | | ||| | |.    .  | |.|  | ||  |   .   
KFGQTIGQGFFGEVYKAYWR-GKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLL--TDHYF

LVLD-WTSRLKVLLDAAKGLDYLHTGCNP-SIIHRDVKSSNILISDKKT-------------GKVADFGLSKMTSEGSSLVSTTVKGTVGYLDPEYYMNQ
...     ...  .| |.|  |||.   |  |.|||  |.|||  .  |              |..|||||.   |. .    |. | . .  || .   
YHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM-GCLCWMAPECFKGE

RLTEKSDVYSFGIVLLETISAREP
  |||.||||||..| . |  ..|
NYTEKVDVYSFGMILWCIITCDQP
Kinase IRAK-0_d-1.AA Dicty5 550-750 33 2.1e-36 122.79 In-house 2-202 (260) Show / Hide 
Range on Protein: 550-750
Range on HMM: 2-202/260
Sequence Identity: 33% (70 aa)

NFGNKIGSGGFGTVYYGRLKNGREVAIKVLSATS--HQGAREFSNEVTLLSRIH--HRNLVSFLGFCQEGRER-ILVYEFMHIGTLRDCLYGKEE-DRLV
 |.  | ||  |.|| |  | |. |||||.|     .    ||  |||..| .   | |.. ..|  |        | |. | |.|.. |  ..      
SFHDWIASGASGRVYNGIYK-GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

LDWTSRLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEGSSLVSTTVKGTVGYLDPEYYMNQRLTEKSDVYSFGIVLLE
. .  .|   .|.|... .||     .|||||.|| |.||    . |. ||| |        .  |.  ||  .  .| .  |  ..| ||||||||| |
IAYFQQLHMAIDIAQSMRHLHSM---NIIHRDLKSMNFLITENWKIKIIDFGTSRFVDN--RYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWE

TISAREP
 .   ||
MFTRKEP
Kinase IRAK-0_d-1.AA TyrKc 549-820 24 5.1e-32 113.6 SMART 1-280 (280) Show / Hide 
Range on Protein: 549-820
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

NNFGNKIGSGGFGTVYYGRLKNGREVAIKVLSATSHQGAREFSNEVTLLSRI--HHRNLVSFLGFCQEG-------RERILVYEFMHIGTLRDCLYGKEE
  .| |.|.| ||.|| |..|  ..||.|.| . .    ..| .|  .....  || |.| ..| | ..           .| |.|  | |.| |  ...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

DRLVLDWTSRLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEG------SSLVST----TVK--GTVGYLDPEYYMNQR
.   | .   |.  ...|.| .|||      .||||    |.|.....| |..|||||.   ..      ..  ..      |    .  . ||  .  .
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

LTEKSDVYSFGIVLLETISAREPLSPELFEPESNIVQWARAALQKGDIKSIVDPALGDAPRM---ESLWKVGEIAMYCVEPHGVNRPTMAEVAREL
 |.||||.|||... |  .  ..  |.  .      | ... ...|.   . . ..   | |   .   .. .|   | .    .|||..|. ...
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAK-0_d-1.AA S_TKc 549-824 22 1.5e-27 98.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 549-824
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

NNFGNKIGSGGFGTVYYGRLKN-GREVAIKVLSATSHQGAREFSNEVTLLSRIHHRNLVSFLGFCQEGRERILVYEFMHI--GTLRDCLYGKEEDR--LV
  ...|||.|.||.|| .| |. ||.||||...       . . .|. .|.. || |.| .....|.  .  .| |..    |.|.| .  .   .   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWTSRLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEGSSLVSTTVKGTVGYLDPEYYMNQRLTE-KSDVYSFGIVLL
..     ...   ...|.|.|   .  |||||.| .|||...  . |..||||..          ||. ||  |. ||       .  |.|..|.|..| 
FPE-HARFYMYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ETISAREPLSPELFEPESNIVQWARAALQKGDIKSIVDPALGDAPRMESLWKVGEIAMYCVEPHGVNRPTMAEVAR-----ELQEAL
| .. . | .        .. .  .  .                    |      . . | .    .|||  |. .      . . .
EMLCGYPPFP--------QMQMMFKKIG--------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-0_d-1.AA ABC1 555-579 42 0.000799 15.14 Pfam 19-44 (126) Show / Hide 
Range on Protein: 555-579
Range on HMM: 19-44/126
Sequence Identity: 42% (11 aa)

IGSGGFGTVYYGRLKN-GREVAIKVL
|...  . |...|||. |.|||.||.
IAAASIAQVHRARLKDDGEEVAVKVQ
Kinase IRAK-0_d-1.AA TK 810-820 36 0.147581 0.12 In-house 476-486 (486) Show / Hide 
Range on Protein: 810-820
Range on HMM: 476-486/486
Sequence Identity: 36% (4 aa)

RPTMAEVAREL
|||.... ..|
RPTFSQLHEQL
Kinase IRAK-0_d-1.AA Dicty4 809-822 25 0.170477 0.95 In-house 262-277 (277) Show / Hide 
Range on Protein: 809-822
Range on HMM: 262-277/277
Sequence Identity: 25% (4 aa)

NRPTMAEVARE--LQE
.||...|.  .  | .
HRPSFEEIIQRRILEH
Kinase IRAK-0_d-1.AA MLK 809-820 25 0.210277 0.79 In-house 280-291 (291) Show / Hide 
Range on Protein: 809-820
Range on HMM: 280-291/291
Sequence Identity: 25% (3 aa)

NRPTMAEVAREL
.||.....  .|
KRPSFRQIVQHL
Kinase IRAK-0_d-1.AA IRAK 809-820 41 0.327227 0.25 In-house 306-317 (317) Show / Hide 
Range on Protein: 809-820
Range on HMM: 306-317/317
Sequence Identity: 41% (5 aa)

NRPTMAEVAREL
.|..||.|  .|
RRCDMAWVMQQL
Kinase IRAK-0_d-1.AA Pkinase_Tyr 809-820 41 5.124829 0.68 Pfam 259-270 (270) Show / Hide 
Range on Protein: 809-820
Range on HMM: 259-270/270
Sequence Identity: 41% (5 aa)

NRPTMAEVAREL
.|||..|. ..|
DRPTFSEIHEQL