Gene IRAK-0_d-2 (S.moellendorffii)

IRAK-0_d-2

Species: S.moellendorffii
Alias: IRAK-0_d-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-0

Sequence

Name Sequence Type Origin Length Description Download
IRAK-0_d-2.AA Protein None 917 None Fasta, JSON
IRAK-0_d-2.NA RNA None 2754 None Fasta, JSON
IRAK-0_d-2.kin_dom Protein Kinase Domain None 193 None Fasta, JSON

Protein domain

Protein domains of IRAK-0_d-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 IRAK-0_d-2.AA LRR_1 413-434 37 0.002724 15.84 Pfam 1-26 (26) Show / Hide 
Range on Protein: 413-434
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

GLNILDLRN-N--SLSGSIPD--MSRL
 | .|||.. |  .|.|.||.     |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-0_d-2.AA LRR_1 436-458 33 0.031106 12.09 Pfam 1-26 (26) Show / Hide 
Range on Protein: 436-458
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

VLRQLHLES-N--RLSGDFPES-LENI
 |. |.| . |  .|.|..|.| . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-0_d-2.AA LRR_1 460-482 40 0.025434 12.4 Pfam 1-26 (26) Show / Hide 
Range on Protein: 460-482
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

TLQLLYLQN-N--LLTGSIPED-LLNR
.|| |.|.. |   |||.||.. . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase IRAK-0_d-2.AA TKL 587-852 21 4.6e-63 215.82 In-house 1-364 (364) Show / Hide 
Range on Protein: 587-852
Range on HMM: 1-364/364
Sequence Identity: 21% (82 aa)

IGSGGFGTVYYGRLKN---------GREVAIKVLSATS--------------------------HQGAREFSNEVT-LLSRIHHRNLVSFLGFCQEGKE-
|||||||.|| |....         |..||.|... ..                           . .|.| .|.. ..||..| |.|.|.|.|....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RILVYEFMHIGT-LRDCLYAKEEDRLVLDWTARLKVLLDAAKGLDYLHT------GCNPSIIHRDVKSSNILISDKKT----------
              .|.|... |. | . .           |  |..  ||.|.|..|||.      .  | ||||| ||.|||. .. |          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----GKVADFGLSKMTSEGSSLVSTT------------------VKGTVGYLDPEYYMNQ----------------RLTEKSDVYSFGIVLLETISAREP
     |..|||||.. |. ..   |                   . || ... ||  ..|                  .||.||||||||| | .. .. 
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-

LSPELFEPESNIVQWARA------ALQKGDIKSIVDPALGDAPR-------MESLWK-VGEIAMYCVEPHGVNRPTMAEVAREL
       |....    .       . ......    | . . ..        .. .. . .... | ..   .||.. |.  .|
-------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-0_d-2.AA Dicty4 582-775 37 1.8e-54 180.18 In-house 2-209 (277) Show / Hide 
Range on Protein: 582-775
Range on HMM: 2-209/277
Sequence Identity: 37% (78 aa)

NFGNKIGSGGFGTVYYGRLKNGREVAIKVL----SATSHQGAREFSNEVTLLSRIHHRNLVSFLGFCQ----EGKERILVYEFMHIGTLRDCLYA---KE
|....||.|.||.|| |. . | |||.|.|       .     || .||.... | | |.. |.| |     .  .   | |.|. |.|   | .     
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

EDRLVLDWTARLK---VLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEGSSLVS--TTVKGTVGYLDPEYYMNQRLTEKSD
 ..  |||. ...     .|||.|. .||. ||| ||||| ||.|.|... .. ||.|||||..  .....    .|..||...  ||  |.|. .||.|
QQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSFGIVLLE
|||||||| |
VYSFGIVLWE
Kinase IRAK-0_d-2.AA IRAK 582-778 34 2.3e-49 170.3 In-house 2-219 (317) Show / Hide 
Range on Protein: 582-778
Range on HMM: 2-219/317
Sequence Identity: 34% (75 aa)

NFGNKIGSGGFGTVYYGRLKNGR-EVAIK----VLSATSHQGAREFSN---EVTLLSRIHHRNLVSFLGFCQEGKERILVYEFMHIGTLRDCLYAKEEDR
. .|.||.||||.|| |..||    .|.|    . . .  .  ..|     |. ...|..| |.|...|.| |. .  |||..|  |.|.| | .   . 
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC

LV--LDWTARLKVLLDAAKGLDYLHTGC-NPSIIHRDVKSSNILISDKKTGKVADFGLSKM---TS--EGSSL---VSTTVKGTVGYLDPEYYM--NQRL
    | |  |..... .|.|. .||.     .|||.|.||.|||  .  | | .||||      .|  | ...      .|.||  |. ||.      .|
PPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQL

TEKSDVYSFGIVLLETIS
| |.|||||||||||...
TKKTDVYSFGIVLLEVLT
Kinase IRAK-0_d-2.AA TKL-Unique 583-775 35 2.3e-48 166.99 In-house 1-220 (290) Show / Hide 
Range on Protein: 583-775
Range on HMM: 1-220/290
Sequence Identity: 35% (79 aa)

FGNKIGSGGFGTVYYGRLKNGREVAIKVLSA---TSHQGAREFSNEVTLLSRIH-HRNLVSFLGFCQ----EGKERILVYEFMHIGTLRDCLY------A
|.||||.||.|.|| |   .| .||||...     | .  .||.|||......| | |.| . |.|       .....| |..  |.|.| |        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

KEEDRLVLDWTARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDK-----KTGKVADFGLSKMTSEGSSLVST--------TVKGTVGYLDPEYY
  .. . |..  |.|  .|.|.|..|||.   | ||||| ||||.|.. .        |..||||||  |  .   ..        |..|.  .. ||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

MN--QRLTEKSDVYSFGIVLLE
..     .|||||||||||| |
RMNFCQYSEKSDVYSFGIVLWE
Kinase IRAK-0_d-2.AA DRK 582-775 37 7e-43 143.08 In-house 2-194 (258) Show / Hide 
Range on Protein: 582-775
Range on HMM: 2-194/258
Sequence Identity: 37% (76 aa)

NFGNKIGSGGFGTVYYGRLKNGREVAIKVLSATSHQ---GAREFSNEVTLLSRIHHRNLVSFLGFCQEGKERILVYEFMHIGTLRDCLYAKEEDRLVLDW
  || || |..| |. |    | .||.| | .          ||  |..|...  | | . |.| | .  .   . |.|  | |   |    .. . .||
KIGNRIGRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH---DESIEMDW

TARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSK----MTSEGSSLVSTTVKGTVGYLDPEYYMNQRLTEKSDVYSFGIVLL
  ...  .|.|||. ||| .||| ||||| || | |. .    ||||||||     . . .      |  || .   ||   ||| ||| |||||.||| 
PLMKQMMFDCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHK---FAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLW

E
|
E
Kinase IRAK-0_d-2.AA LRRK 581-773 27 8.4e-40 138.49 In-house 1-272 (351) Show / Hide 
Range on Protein: 581-773
Range on HMM: 1-272/351
Sequence Identity: 27% (75 aa)

NNFGNKIGSGGFG-TVYYGRLKN---------------------------GREVAIKVLSAT----------------------------------SHQG
  ....||.|||| .|| .....                           . .||||..  .                                  ..  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

AREFSNEVTLLSRIHHRNLVSFLGFCQEGKERILVYEFMHIGTLRDCLYAKEEDRL-----VLDWTARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNI
 ||| .||...|. .| |.|| .||| .   ...| |.. .|.| . | .|..|..     ...|. .||. |. |||..|||  .||.||||| || ||
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LI-SDK-----------KTGKVADFGLSK-MTSEGSSLVSTTVKGTVGYLDPEYYMNQ---RLTEKSDVYSFGIVL
|. | .            . |.||||.|   .. ....... | |. |.. ||   .      |||.|.||||..|
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV-GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Pkinase IRAK-0_d-2.AA Pkinase 581-794 26 6.2e-39 138.74 Pfam 1-221 (293) Show / Hide 
Range on Protein: 581-794
Range on HMM: 1-221/293
Sequence Identity: 26% (61 aa)

NNFGNKIGSGGFGTVYYGRLKNGRE-VAIKVLSATSHQGAREFSN-----EVTLLSRIHHRNLVSFLGFCQEGKERILVYEFMHIG----TLRDCLYAKE
  .| |||||.||.|| .. |. .. ||.|...   |.   .  .     |. .. |..| | | ..........  .| |..  |     | | . ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

EDRLVLDWTARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTG----KVADFGLSK-MTSEGSSLVSTTVKGTVGYLDPEYYM-NQRLTEKS
. .. ...    ....  ..||.|.|  .  .|||||.|..||||... .     |..||||.| .  . ..   ||. || .|. ||  . .|  . |.
HGCFYFSEWECKFYMYQILRGLEYCHS-M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSFGIVLLETISAREPLSPELFEPESNI
|..|.|..| | .. | | . .   ... .
DMWSCGCILYEMLCGRPPFPGHC-WHDN-H
Kinase IRAK-0_d-2.AA Pkinase_Tyr 582-782 28 7.1e-38 128.89 Pfam 2-214 (270) Show / Hide 
Range on Protein: 582-782
Range on HMM: 2-214/270
Sequence Identity: 28% (62 aa)

NFGNKIGSGGFGTVYYGRLK-----NGREVAIKVLSATSHQGA---REFSNEVTLLSRI-HHRNLVSFLGFCQ-EGKE--RILVYEFMHIGTLRDCLYAK
 || |.|.| ||.|| |..|     .. .||.|.|  .... .   ..| .|. ... . || |.|...| |  .|.    ..| |.|  | |.| | ..
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

--EEDRLVLDWTARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMT-SEGSS-LVSTTVKGTVGYLDPEYYMNQRLTEKSD
  ....| . .   |.  .. |||..||.      .||||.   |.|...... |..||||..   ...    ...  |  .  . ||  .. . |.|||
REDKQPLTMKD--LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VYSFGIVLLETIS-AREP
|.|||... | ..  ..|
VWSFGVLMWEIFTYGEQP
Kinase IRAK-0_d-2.AA Dicty5 582-782 33 4.1e-37 125.28 In-house 2-202 (260) Show / Hide 
Range on Protein: 582-782
Range on HMM: 2-202/260
Sequence Identity: 33% (70 aa)

NFGNKIGSGGFGTVYYGRLKNGREVAIKVLSATS--HQGAREFSNEVTLLSRIH--HRNLVSFLGFCQEGKER-ILVYEFMHIGTLRDCLYAKEE-DRLV
 |.  | ||  |.|| |  | |. |||||.|     .    ||  |||..| .   | |.. ..|  |  .     | |. | |.|.. |  ..      
SFHDWIASGASGRVYNGIYK-GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

LDWTARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEGSSLVSTTVKGTVGYLDPEYYMNQRLTEKSDVYSFGIVLLE
. .  .|   .|.|... .||     .|||||.|| |.||    . |. ||| |        .  |.  ||  .  .| .  |  ..| ||||||||| |
IAYFQQLHMAIDIAQSMRHLHSM---NIIHRDLKSMNFLITENWKIKIIDFGTSRFVDN--RYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWE

TISAREP
 .   ||
MFTRKEP
Kinase IRAK-0_d-2.AA CZAK 582-782 32 6.8e-37 128.89 In-house 2-221 (279) Show / Hide 
Range on Protein: 582-782
Range on HMM: 2-221/279
Sequence Identity: 32% (73 aa)

NFGNKIGSGGFGTVYYGRLKNGREVAIKVLSATSHQGARE------FSNEVTLLSRIHHRNLVSFLGFCQEGK--ERILVYEFMHIGTLRDCLYAKEEDR
 ||  || | || || .. . |  |||| .   .     |      | .||  .|   | | | ||| | |.    .  | |.|  | ||  |   .   
KFGQTIGQGFFGEVYKAYWR-GKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLL--TDHYF

LVLD-WTARLKVLLDAAKGLDYLHTGCNP-SIIHRDVKSSNILISDKKT-------------GKVADFGLSKMTSEGSSLVSTTVKGTVGYLDPEYYMNQ
...     ...  .| |.|  |||.   |  |.|||  |.|||  .  |              |..|||||.   |. .    |. | . .  || .   
YHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM-GCLCWMAPECFKGE

RLTEKSDVYSFGIVLLETISAREP
  |||.||||||..| . |  ..|
NYTEKVDVYSFGMILWCIITCDQP
Kinase IRAK-0_d-2.AA MLK 581-782 28 1.7e-36 124.18 In-house 1-235 (291) Show / Hide 
Range on Protein: 581-782
Range on HMM: 1-235/291
Sequence Identity: 28% (68 aa)

NNFGNKIGSGGFGTVYYGRLKNGR----EVAIKVLS------ATSHQGAREFSNEVTLLSRIHHRN----LVSFLGFCQE-GKERILVYEFMHIGTLRDC
 .|  .||||.|| |. || .| .    .||.|         . .   ...|  |. .|... |.|     . |.| |.. ...  .| |..  | | . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LYA---KEEDR-------LVLDWTARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISD------KKTGKVADFGLSKMTSEGSSLVSTTVKGTVGY
|..   |..|.        | |    ..  |. |.|..|||    . ||||| ||.||||..      ..| |..|||.|.. ..      .  .||. .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

LDPEYY---MNQRLTEKSDVYSFGIVLLETISAREP
  ||      ... .||.||.|.|.|| | .. ..|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAK-0_d-2.AA Dicty4-Unclassified 582-782 34 2.8e-36 121.74 In-house 2-207 (263) Show / Hide 
Range on Protein: 582-782
Range on HMM: 2-207/263
Sequence Identity: 34% (73 aa)

NFGNKIGSGGFGTVYYGRLKNGREVAIKVLSATSHQGAR-----EFSNEVTLLSRIHHRNLVSFLGFCQEG----KERILVYEFMHIGTLRDCLY---AK
     || | |  |. |  | |..||.| .   . . .|     .|  || .|  | | |||   | |          . | |||| |.|        . 
QIDQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFK-FREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

EEDRLVLDWTARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEGSSLVSTTVKGTVGYLDPEYYMNQRLTEKSDVYSF
 .  . || |  .|. .| |.|. .|||     .||||.||||||.      |.||||.|  ..    .  ||. ||.    ||  |    . ||||||.
QQQPIKLDDTLIIKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNM--TTIAGTPKWESPECLMHESYNQKSDVYSY

GIVLLETISAREP
...| | .   ||
AMMLYELATGDEP
Kinase IRAK-0_d-2.AA TyrKc 581-852 24 4.9e-33 117.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 581-852
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

NNFGNKIGSGGFGTVYYGRLKNGREVAIKVLSATSHQGAREFSNEVTLLSRI--HHRNLVSFLGFCQEG-------KERILVYEFMHIGTLRDCLYAKEE
  .| |.|.| ||.|| |..|  ..||.|.| . .    ..| .|  .....  || |.| ..| | ..       .   .| |.|  | |.| | ....
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

DRLVLDWTARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEG------SSLVST----TVK--GTVGYLDPEYYMNQR
.   | .   |.  ...|.| .|||      .||||    |.|.....| |..|||||.   ..      ..  ..      |    .  . ||  .  .
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

LTEKSDVYSFGIVLLETISAREPLSPELFEPESNIVQWARAALQKGDIKSIVDPALGDAPRM---ESLWKVGEIAMYCVEPHGVNRPTMAEVAREL
 |.||||.|||... |  .  ..  |.  .      | ... ...|.   . . ..   | |   .   .. .|   | .    .|||..|. ...
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAK-0_d-2.AA S_TKc 581-856 22 8.2e-29 102.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 581-856
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

NNFGNKIGSGGFGTVYYGRLKN-GREVAIKVLSATSHQGAREFSNEVTLLSRIHHRNLVSFLGFCQEGKERILVYEFMHI--GTLRDCLYAKEEDR--LV
  ...|||.|.||.|| .| |. ||.||||...       . . .|. .|.. || |.| .....|. ..  .| |..    |.|.| .  .   .   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWTARLKVLLDAAKGLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEGSSLVSTTVKGTVGYLDPEYYMNQRLTE-KSDVYSFGIVLL
..     ...   ...|.|.|   .  |||||.| .|||...  . |..||||..          ||. ||  |. ||       .  |.|..|.|..| 
FPE-HARFYMYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ETISAREPLSPELFEPESNIVQWARAALQKGDIKSIVDPALGDAPRMESLWKVGEIAMYCVEPHGVNRPTMAEVAR-----ELQEAL
| .. . | .        .. .  .  .                    |      . . | .    .|||  |. .      . . .
EMLCGYPPFP--------QMQMMFKKIG--------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-0_d-2.AA ABC1 587-611 42 0.000799 15.14 Pfam 19-44 (126) Show / Hide 
Range on Protein: 587-611
Range on HMM: 19-44/126
Sequence Identity: 42% (11 aa)

IGSGGFGTVYYGRLKN-GREVAIKVL
|...  . |...|||. |.|||.||.
IAAASIAQVHRARLKDDGEEVAVKVQ
Kinase IRAK-0_d-2.AA Dicty4 841-854 25 0.170477 0.95 In-house 262-277 (277) Show / Hide 
Range on Protein: 841-854
Range on HMM: 262-277/277
Sequence Identity: 25% (4 aa)

NRPTMAEVARE--LQE
.||...|.  .  | .
HRPSFEEIIQRRILEH
Kinase IRAK-0_d-2.AA MLK 841-852 25 0.210277 0.79 In-house 280-291 (291) Show / Hide 
Range on Protein: 841-852
Range on HMM: 280-291/291
Sequence Identity: 25% (3 aa)

NRPTMAEVAREL
.||.....  .|
KRPSFRQIVQHL
Kinase IRAK-0_d-2.AA IRAK 841-852 41 0.327227 0.25 In-house 306-317 (317) Show / Hide 
Range on Protein: 841-852
Range on HMM: 306-317/317
Sequence Identity: 41% (5 aa)

NRPTMAEVAREL
.|..||.|  .|
RRCDMAWVMQQL
Kinase IRAK-0_d-2.AA Pkinase_Tyr 841-852 41 5.124829 0.68 Pfam 259-270 (270) Show / Hide 
Range on Protein: 841-852
Range on HMM: 259-270/270
Sequence Identity: 41% (5 aa)

NRPTMAEVAREL
.|||..|. ..|
DRPTFSEIHEQL